The function of RNA-binding proteins at the synapse: implications for neurodegeneration
Identifieur interne : 000501 ( Main/Exploration ); précédent : 000500; suivant : 000502The function of RNA-binding proteins at the synapse: implications for neurodegeneration
Auteurs : Chantelle F. Sephton ; Gang Yu [États-Unis]Source :
- Cellular and Molecular Life Sciences [ 1420-682X ] ; 2015.
Abstract
The loss of synapses is a central event in neurodegenerative diseases. Synaptic proteins are often associated with disease neuropathology, but their role in synaptic loss is not fully understood. Of the many processes involved in sustaining the integrity of synapses, local protein translation can directly impact synaptic formation, communication, and maintenance. RNA-binding proteins and their association with RNA granules serve to regulate mRNA transportation and translation at synapses and in turn regulate the synapse. Genetic mutations in RNA-binding proteins FUS and TDP-43 have been linked with causing neurodegenerative diseases: amyotrophic lateral sclerosis and frontotemporal dementia. The observation that mutations in FUS and TDP-43 coincide with changes in RNA granules provides evidence that dysfunction of RNA metabolism may underlie the mechanism of synaptic loss in these diseases. However, we do not know how mutations in RNA-binding proteins would affect RNA granule dynamics and local translation, or if these alterations would cause neurodegeneration. Further investigation into this area will lead to important insights into how disruption of RNA metabolism and local translation at synapses can cause neurodegenerative diseases.
Url:
DOI: 10.1007/s00018-015-1943-x
PubMed: 26047658
PubMed Central: 4565867
Affiliations:
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The function of RNA-binding proteins at the synapse: implications for neurodegeneration</title><author><name sortKey="Sephton, Chantelle F" sort="Sephton, Chantelle F" uniqKey="Sephton C" first="Chantelle F." last="Sephton">Chantelle F. Sephton</name><affiliation><nlm:aff id="Aff1">Department of Psychiatry and Neuroscience, Institut Universitaire En Santé Mentale de Québec, Université Laval, Quebec, QC G1J 2G3 Canada</nlm:aff><wicri:noCountry code="subfield">QC G1J 2G3 Canada</wicri:noCountry></affiliation></author><author><name sortKey="Yu, Gang" sort="Yu, Gang" uniqKey="Yu G" first="Gang" last="Yu">Gang Yu</name><affiliation wicri:level="2"><nlm:aff id="Aff2">Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX 75390 USA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Texas</region></placeName><wicri:cityArea>Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas</wicri:cityArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">26047658</idno><idno type="pmc">4565867</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565867</idno><idno type="RBID">PMC:4565867</idno><idno type="doi">10.1007/s00018-015-1943-x</idno><date when="2015">2015</date><idno type="wicri:Area/Pmc/Corpus">000278</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000278</idno><idno type="wicri:Area/Pmc/Curation">000278</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000278</idno><idno type="wicri:Area/Pmc/Checkpoint">000195</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000195</idno><idno type="wicri:Area/Ncbi/Merge">001B89</idno><idno type="wicri:Area/Ncbi/Curation">001B89</idno><idno type="wicri:Area/Ncbi/Checkpoint">001B89</idno><idno type="wicri:doubleKey">1420-682X:2015:Sephton C:the:function:of</idno><idno type="wicri:Area/Main/Merge">000502</idno><idno type="wicri:Area/Main/Curation">000501</idno><idno type="wicri:Area/Main/Exploration">000501</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">The function of RNA-binding proteins at the synapse: implications for neurodegeneration</title><author><name sortKey="Sephton, Chantelle F" sort="Sephton, Chantelle F" uniqKey="Sephton C" first="Chantelle F." last="Sephton">Chantelle F. Sephton</name><affiliation><nlm:aff id="Aff1">Department of Psychiatry and Neuroscience, Institut Universitaire En Santé Mentale de Québec, Université Laval, Quebec, QC G1J 2G3 Canada</nlm:aff><wicri:noCountry code="subfield">QC G1J 2G3 Canada</wicri:noCountry></affiliation></author><author><name sortKey="Yu, Gang" sort="Yu, Gang" uniqKey="Yu G" first="Gang" last="Yu">Gang Yu</name><affiliation wicri:level="2"><nlm:aff id="Aff2">Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX 75390 USA</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Texas</region></placeName><wicri:cityArea>Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas</wicri:cityArea></affiliation></author></analytic><series><title level="j">Cellular and Molecular Life Sciences</title><idno type="ISSN">1420-682X</idno><idno type="eISSN">1420-9071</idno><imprint><date when="2015">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>The loss of synapses is a central event in
neurodegenerative diseases. Synaptic proteins are often associated with disease neuropathology, but their role in synaptic loss is not fully understood. Of the many processes involved in sustaining the integrity of synapses, local protein translation can directly impact synaptic formation, communication, and maintenance. RNA-binding proteins and their association with RNA granules serve to regulate mRNA transportation and translation at synapses and in turn regulate the synapse. Genetic mutations in RNA-binding proteins FUS and TDP-43 have been linked with causing neurodegenerative diseases: amyotrophic lateral sclerosis and frontotemporal dementia. The observation that mutations in FUS and TDP-43 coincide with changes in RNA granules provides evidence that dysfunction of RNA metabolism may underlie the mechanism of synaptic loss in these diseases. However, we do not know how mutations in RNA-binding proteins would affect RNA granule dynamics and local translation, or if these alterations would cause neurodegeneration. Further investigation into this area will lead to important insights into how disruption of RNA metabolism and local translation at synapses can cause neurodegenerative diseases.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Dever, Te" uniqKey="Dever T">TE Dever</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van Langenhove, T" uniqKey="Van Langenhove T">T Van Langenhove</name></author><author><name sortKey="Van Der Zee, J" uniqKey="Van Der Zee J">J van der Zee</name></author><author><name sortKey="Van Broeckhoven, C" uniqKey="Van Broeckhoven C">C Van Broeckhoven</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kiernan, Mc" uniqKey="Kiernan M">MC Kiernan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Snowden, Js" uniqKey="Snowden J">JS Snowden</name></author><author><name sortKey="Neary, D" uniqKey="Neary D">D Neary</name></author><author><name sortKey="Mann, Dm" uniqKey="Mann D">DM Mann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Strong, Mj" uniqKey="Strong M">MJ Strong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dormann, D" uniqKey="Dormann D">D Dormann</name></author><author><name sortKey="Haass, C" uniqKey="Haass C">C Haass</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lee, Eb" uniqKey="Lee E">EB Lee</name></author><author><name sortKey="Lee, Vm" uniqKey="Lee V">VM Lee</name></author><author><name sortKey="Trojanowski, Jq" uniqKey="Trojanowski J">JQ Trojanowski</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Steward, O" uniqKey="Steward O">O Steward</name></author><author><name sortKey="Levy, Wb" uniqKey="Levy W">WB Levy</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sutton, Ma" uniqKey="Sutton M">MA Sutton</name></author><author><name sortKey="Schuman, Em" uniqKey="Schuman E">EM Schuman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Klann, E" uniqKey="Klann E">E Klann</name></author><author><name sortKey="Dever, Te" uniqKey="Dever T">TE Dever</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Willis, D" uniqKey="Willis D">D Willis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Anderson, P" uniqKey="Anderson P">P Anderson</name></author><author><name sortKey="Kedersha, N" uniqKey="Kedersha N">N Kedersha</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Buchan, Jr" uniqKey="Buchan J">JR Buchan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Anderson, P" uniqKey="Anderson P">P Anderson</name></author><author><name sortKey="Kedersha, N" uniqKey="Kedersha N">N Kedersha</name></author><author><name sortKey="Ivanov, P" uniqKey="Ivanov P">P Ivanov</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Martin, Kc" uniqKey="Martin K">KC Martin</name></author><author><name sortKey="Ephrussi, A" uniqKey="Ephrussi A">A Ephrussi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Richter, Jd" uniqKey="Richter J">JD Richter</name></author><author><name sortKey="Klann, E" uniqKey="Klann E">E Klann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zeitelhofer, M" uniqKey="Zeitelhofer M">M Zeitelhofer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Xing, L" uniqKey="Xing L">L Xing</name></author><author><name sortKey="Bassell, Gj" uniqKey="Bassell G">GJ Bassell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kiebler, Ma" uniqKey="Kiebler M">MA Kiebler</name></author><author><name sortKey="Bassell, Gj" uniqKey="Bassell G">GJ Bassell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Baez, Mv" uniqKey="Baez M">MV Baez</name></author><author><name sortKey="Boccaccio, Gl" uniqKey="Boccaccio G">GL Boccaccio</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Vessey, Jp" uniqKey="Vessey J">JP Vessey</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, If" uniqKey="Wang I">IF Wang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kanai, Y" uniqKey="Kanai Y">Y Kanai</name></author><author><name sortKey="Dohmae, N" uniqKey="Dohmae N">N Dohmae</name></author><author><name sortKey="Hirokawa, N" uniqKey="Hirokawa N">N Hirokawa</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Belly, A" uniqKey="Belly A">A Belly</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Marko, M" uniqKey="Marko M">M Marko</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mikl, M" uniqKey="Mikl M">M Mikl</name></author><author><name sortKey="Vendra, G" uniqKey="Vendra G">G Vendra</name></author><author><name sortKey="Kiebler, Ma" uniqKey="Kiebler M">MA Kiebler</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Anderson, P" uniqKey="Anderson P">P Anderson</name></author><author><name sortKey="Kedersha, N" uniqKey="Kedersha N">N Kedersha</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mollet, S" uniqKey="Mollet S">S Mollet</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dewey, Cm" uniqKey="Dewey C">CM Dewey</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Buchan, Jr" uniqKey="Buchan J">JR Buchan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nover, L" uniqKey="Nover L">L Nover</name></author><author><name sortKey="Scharf, Kd" uniqKey="Scharf K">KD Scharf</name></author><author><name sortKey="Neumann, D" uniqKey="Neumann D">D Neumann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kedersha, N" uniqKey="Kedersha N">N Kedersha</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kedersha, N" uniqKey="Kedersha N">N Kedersha</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kedersha, N" uniqKey="Kedersha N">N Kedersha</name></author><author><name sortKey="Ivanov, P" uniqKey="Ivanov P">P Ivanov</name></author><author><name sortKey="Anderson, P" uniqKey="Anderson P">P Anderson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bosco, Da" uniqKey="Bosco D">DA Bosco</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nonhoff, U" uniqKey="Nonhoff U">U Nonhoff</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Emara, Mm" uniqKey="Emara M">MM Emara</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Andersson, Mk" uniqKey="Andersson M">MK Andersson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kim, Hj" uniqKey="Kim H">HJ Kim</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hua, Y" uniqKey="Hua Y">Y Hua</name></author><author><name sortKey="Zhou, J" uniqKey="Zhou J">J Zhou</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shelkovnikova, Ta" uniqKey="Shelkovnikova T">TA Shelkovnikova</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cougot, N" uniqKey="Cougot N">N Cougot</name></author><author><name sortKey="Babajko, S" uniqKey="Babajko S">S Babajko</name></author><author><name sortKey="Seraphin, B" uniqKey="Seraphin B">B Seraphin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bhattacharyya, Sn" uniqKey="Bhattacharyya S">SN Bhattacharyya</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Antar, Ln" uniqKey="Antar L">LN Antar</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brengues, M" uniqKey="Brengues M">M Brengues</name></author><author><name sortKey="Teixeira, D" uniqKey="Teixeira D">D Teixeira</name></author><author><name sortKey="Parker, R" uniqKey="Parker R">R Parker</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van Dijk, E" uniqKey="Van Dijk E">E van Dijk</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Giorgi, C" uniqKey="Giorgi C">C Giorgi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mallardo, M" uniqKey="Mallardo M">M Mallardo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Krichevsky, Am" uniqKey="Krichevsky A">AM Krichevsky</name></author><author><name sortKey="Kosik, Ks" uniqKey="Kosik K">KS Kosik</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhang, Hl" uniqKey="Zhang H">HL Zhang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Huttelmaier, S" uniqKey="Huttelmaier S">S Huttelmaier</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stebbins Boaz, B" uniqKey="Stebbins Boaz B">B Stebbins-Boaz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Barnard, Dc" uniqKey="Barnard D">DC Barnard</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kim, Jh" uniqKey="Kim J">JH Kim</name></author><author><name sortKey="Richter, Jd" uniqKey="Richter J">JD Richter</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cao, Q" uniqKey="Cao Q">Q Cao</name></author><author><name sortKey="Richter, Jd" uniqKey="Richter J">JD Richter</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wu, L" uniqKey="Wu L">L Wu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wells, Dg" uniqKey="Wells D">DG Wells</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Garber, K" uniqKey="Garber K">K Garber</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nalavadi, Vc" uniqKey="Nalavadi V">VC Nalavadi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Darnell, Jc" uniqKey="Darnell J">JC Darnell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Miyashiro, Ky" uniqKey="Miyashiro K">KY Miyashiro</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brown, V" uniqKey="Brown V">V Brown</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bassell, Gj" uniqKey="Bassell G">GJ Bassell</name></author><author><name sortKey="Warren, St" uniqKey="Warren S">ST Warren</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Khandjian, Ew" uniqKey="Khandjian E">EW Khandjian</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stefani, G" uniqKey="Stefani G">G Stefani</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zalfa, F" uniqKey="Zalfa F">F Zalfa</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Siomi, Mc" uniqKey="Siomi M">MC Siomi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Narayanan, U" uniqKey="Narayanan U">U Narayanan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ceman, S" uniqKey="Ceman S">S Ceman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jin, P" uniqKey="Jin P">P Jin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Muddashetty, Rs" uniqKey="Muddashetty R">RS Muddashetty</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Darnell, Jc" uniqKey="Darnell J">JC Darnell</name></author><author><name sortKey="Klann, E" uniqKey="Klann E">E Klann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fischer, Lr" uniqKey="Fischer L">LR Fischer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Petkau, Tl" uniqKey="Petkau T">TL Petkau</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kaufmann, We" uniqKey="Kaufmann W">WE Kaufmann</name></author><author><name sortKey="Moser, Hw" uniqKey="Moser H">HW Moser</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Eiland, L" uniqKey="Eiland L">L Eiland</name></author><author><name sortKey="Mcewen, Bs" uniqKey="Mcewen B">BS McEwen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Soetanto, A" uniqKey="Soetanto A">A Soetanto</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stephan, Ke" uniqKey="Stephan K">KE Stephan</name></author><author><name sortKey="Baldeweg, T" uniqKey="Baldeweg T">T Baldeweg</name></author><author><name sortKey="Friston, Kj" uniqKey="Friston K">KJ Friston</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Calabresi, P" uniqKey="Calabresi P">P Calabresi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Blanpied, Ta" uniqKey="Blanpied T">TA Blanpied</name></author><author><name sortKey="Ehlers, Md" uniqKey="Ehlers M">MD Ehlers</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bourne, Jn" uniqKey="Bourne J">JN Bourne</name></author><author><name sortKey="Harris, Km" uniqKey="Harris K">KM Harris</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sephton, Cf" uniqKey="Sephton C">CF Sephton</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Qiu, H" uniqKey="Qiu H">H Qiu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dolen, G" uniqKey="Dolen G">G Dolen</name></author><author><name sortKey="Bear, Mf" uniqKey="Bear M">MF Bear</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Irwin, Sa" uniqKey="Irwin S">SA Irwin</name></author><author><name sortKey="Galvez, R" uniqKey="Galvez R">R Galvez</name></author><author><name sortKey="Greenough, Wt" uniqKey="Greenough W">WT Greenough</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Savas, Jn" uniqKey="Savas J">JN Savas</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Villace, P" uniqKey="Villace P">P Villace</name></author><author><name sortKey="Marion, Rm" uniqKey="Marion R">RM Marion</name></author><author><name sortKey="Ortin, J" uniqKey="Ortin J">J Ortin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Vessey, Jp" uniqKey="Vessey J">JP Vessey</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Goetze, B" uniqKey="Goetze B">B Goetze</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fujii, R" uniqKey="Fujii R">R Fujii</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lefebvre, S" uniqKey="Lefebvre S">S Lefebvre</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Corcia, P" uniqKey="Corcia P">P Corcia</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Coovert, Dd" uniqKey="Coovert D">DD Coovert</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Elden, Ac" uniqKey="Elden A">AC Elden</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pulst, Sm" uniqKey="Pulst S">SM Pulst</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chen, Yz" uniqKey="Chen Y">YZ Chen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Greenway, Mj" uniqKey="Greenway M">MJ Greenway</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van Es, Ma" uniqKey="Van Es M">MA van Es</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Neumann, M" uniqKey="Neumann M">M Neumann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Couthouis, J" uniqKey="Couthouis J">J Couthouis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Couthouis, J" uniqKey="Couthouis J">J Couthouis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ticozzi, N" uniqKey="Ticozzi N">N Ticozzi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Doi, H" uniqKey="Doi H">H Doi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schwab, C" uniqKey="Schwab C">C Schwab</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Amador Ortiz, C" uniqKey="Amador Ortiz C">C Amador-Ortiz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tan, Ay" uniqKey="Tan A">AY Tan</name></author><author><name sortKey="Manley, Jl" uniqKey="Manley J">JL Manley</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ishigaki, S" uniqKey="Ishigaki S">S Ishigaki</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rogelj, B" uniqKey="Rogelj B">B Rogelj</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hoell, Ji" uniqKey="Hoell J">JI Hoell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lagier Tourenne, C" uniqKey="Lagier Tourenne C">C Lagier-Tourenne</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lerga, A" uniqKey="Lerga A">A Lerga</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bentmann, E" uniqKey="Bentmann E">E Bentmann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Iko, Y" uniqKey="Iko Y">Y Iko</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tsuiji, H" uniqKey="Tsuiji H">H Tsuiji</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ling, Sc" uniqKey="Ling S">SC Ling</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Calvio, C" uniqKey="Calvio C">C Calvio</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kameoka, S" uniqKey="Kameoka S">S Kameoka</name></author><author><name sortKey="Duque, P" uniqKey="Duque P">P Duque</name></author><author><name sortKey="Konarska, Mm" uniqKey="Konarska M">MM Konarska</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Morlando, M" uniqKey="Morlando M">M Morlando</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rappsilber, J" uniqKey="Rappsilber J">J Rappsilber</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhou, Z" uniqKey="Zhou Z">Z Zhou</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gregory, Ri" uniqKey="Gregory R">RI Gregory</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kwon, I" uniqKey="Kwon I">I Kwon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schwartz, Jc" uniqKey="Schwartz J">JC Schwartz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lee, Bj" uniqKey="Lee B">BJ Lee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yasuda, K" uniqKey="Yasuda K">K Yasuda</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Reschke, M" uniqKey="Reschke M">M Reschke</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bentmann, E" uniqKey="Bentmann E">E Bentmann</name></author><author><name sortKey="Haass, C" uniqKey="Haass C">C Haass</name></author><author><name sortKey="Dormann, D" uniqKey="Dormann D">D Dormann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dormann, D" uniqKey="Dormann D">D Dormann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sabatelli, M" uniqKey="Sabatelli M">M Sabatelli</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, Wy" uniqKey="Wang W">WY Wang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lanson, Na" uniqKey="Lanson N">NA Lanson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Murakami, T" uniqKey="Murakami T">T Murakami</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Huang, C" uniqKey="Huang C">C Huang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Huang, C" uniqKey="Huang C">C Huang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shahidullah, M" uniqKey="Shahidullah M">M Shahidullah</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Baron, Dm" uniqKey="Baron D">DM Baron</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Takanashi, K" uniqKey="Takanashi K">K Takanashi</name></author><author><name sortKey="Yamaguchi, A" uniqKey="Yamaguchi A">A Yamaguchi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Krecic, Am" uniqKey="Krecic A">AM Krecic</name></author><author><name sortKey="Swanson, Ms" uniqKey="Swanson M">MS Swanson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Polymenidou, M" uniqKey="Polymenidou M">M Polymenidou</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tollervey, Jr" uniqKey="Tollervey J">JR Tollervey</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sephton, Cf" uniqKey="Sephton C">CF Sephton</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ou, Sh" uniqKey="Ou S">SH Ou</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Buratti, E" uniqKey="Buratti E">E Buratti</name></author><author><name sortKey="Baralle, Fe" uniqKey="Baralle F">FE Baralle</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Buratti, E" uniqKey="Buratti E">E Buratti</name></author><author><name sortKey="Baralle, Fe" uniqKey="Baralle F">FE Baralle</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kawahara, Y" uniqKey="Kawahara Y">Y Kawahara</name></author><author><name sortKey="Mieda Sato, A" uniqKey="Mieda Sato A">A Mieda-Sato</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chendrimada, Tp" uniqKey="Chendrimada T">TP Chendrimada</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Freibaum, Bd" uniqKey="Freibaum B">BD Freibaum</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Winton, Mj" uniqKey="Winton M">MJ Winton</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dewey, Cm" uniqKey="Dewey C">CM Dewey</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Moisse, K" uniqKey="Moisse K">K Moisse</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Colombrita, C" uniqKey="Colombrita C">C Colombrita</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Liu Yesucevitz, L" uniqKey="Liu Yesucevitz L">L Liu-Yesucevitz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Barbee, Sa" uniqKey="Barbee S">SA Barbee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gregory, Ri" uniqKey="Gregory R">RI Gregory</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Neumann, M" uniqKey="Neumann M">M Neumann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mackenzie, Ir" uniqKey="Mackenzie I">IR Mackenzie</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gitcho, Ma" uniqKey="Gitcho M">MA Gitcho</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ayala, Ym" uniqKey="Ayala Y">YM Ayala</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fuentealba, Ra" uniqKey="Fuentealba R">RA Fuentealba</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cushman, M" uniqKey="Cushman M">M Cushman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Swarup, V" uniqKey="Swarup V">V Swarup</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wils, H" uniqKey="Wils H">H Wils</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wegorzewska, I" uniqKey="Wegorzewska I">I Wegorzewska</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sephton, Cf" uniqKey="Sephton C">CF Sephton</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wu, Ls" uniqKey="Wu L">LS Wu</name></author><author><name sortKey="Cheng, Wc" uniqKey="Cheng W">WC Cheng</name></author><author><name sortKey="Shen, Ck" uniqKey="Shen C">CK Shen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fiesel, Fc" uniqKey="Fiesel F">FC Fiesel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Feiguin, F" uniqKey="Feiguin F">F Feiguin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lu, Y" uniqKey="Lu Y">Y Lu</name></author><author><name sortKey="Ferris, J" uniqKey="Ferris J">J Ferris</name></author><author><name sortKey="Gao, Fb" uniqKey="Gao F">FB Gao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lin, Mj" uniqKey="Lin M">MJ Lin</name></author><author><name sortKey="Cheng, Cw" uniqKey="Cheng C">CW Cheng</name></author><author><name sortKey="Shen, Ck" uniqKey="Shen C">CK Shen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, Y" uniqKey="Li Y">Y Li</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kabashi, E" uniqKey="Kabashi E">E Kabashi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Han, Jh" uniqKey="Han J">JH Han</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Majumder, P" uniqKey="Majumder P">P Majumder</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Colombrita, C" uniqKey="Colombrita C">C Colombrita</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Alami, Nh" uniqKey="Alami 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Sephton</name></noCountry><country name="États-Unis"><region name="Texas"><name sortKey="Yu, Gang" sort="Yu, Gang" uniqKey="Yu G" first="Gang" last="Yu">Gang Yu</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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